Pathological Relationship between Intracellular Superoxide Metabolism and p53 Signaling in Mice

Pathological Relationship between Intracellular Superoxide Metabolism and p53 Signaling in Mice

Intracellular superoxide dismutases (SODs) maintain tissue homeostasis via superoxide metabolism. We previously reported that intracellular reactive oxygen species (ROS), including superoxide accumulation caused by cytoplasmic SOD (SOD1) or mitochondrial SOD (SOD2) insufficiency, induced p53 activat...

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Bibliographic Details
Main Authors: Kenji Watanabe, Shuichi Shibuya, Yusuke Ozawa, Toshihiko Toda, Takahiko Shimizu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
superoxide dismutase (SOD)
p53
superoxide
aging
apoptosis
Online Access:https://www.mdpi.com/1422-0067/22/7/3548

Internet

https://www.mdpi.com/1422-0067/22/7/3548

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