Novel hepatotoxicity biomarkers of extracellular vesicle (EV)-associated miRNAs induced by CCl4

Novel hepatotoxicity biomarkers of extracellular vesicle (EV)-associated miRNAs induced by CCl4

Recent findings have revealed that extracellular vesicles (EVs) are secreted from cells and circulate in the blood. EVs are classified as exosomes (40−100 nm), microvesicles (50−1,000 nm) or apoptotic bodies (500−2,000 nm). EVs contain mRNAs, microRNAs, and DNAs and have the ability to transfer them...

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Bibliographic Details
Main Authors: Ryuichi Ono, Yusuke Yoshioka, Yusuke Furukawa, Mie Naruse, Makiko Kuwagata, Takahiro Ochiya, Satoshi Kitajima, Yoko Hirabayashi
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
Exosome
Extracellular vesicle
EV
Hepatotoxicity
miRNA
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750020300664

Internet

http://www.sciencedirect.com/science/article/pii/S2214750020300664

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