mir15a/mir16‐1 cluster and its novel targeting molecules negatively regulate cardiac hypertrophy

Abstract In response to pathological stimuli, the heart develops ventricular hypertrophy that progressively decompensates and leads to heart failure. miRNAs are increasingly recognized as pathogenic factors, clinically relevant biomarkers, and potential therapeutic targets. We identified that mir15a...

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Bibliographic Details
Main Authors: Hongchang Guo, Ke Ma, Wenjing Hao, Yao Jiao, Ping Li, Jing Chen, Chen Xu, Fu‐jian Xu, Wayne Bond Lau, Jie Du, Xin‐liang Ma, Yulin Li
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.242