Drug Retention Rate and Predictive Factors of Drug Survival for Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis

Drug Retention Rate and Predictive Factors of Drug Survival for Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis

Background and Objectives: Few studies have reported the drug retention rate (DRR) of biologic drugs in juvenile idiopathic arthritis (JIA), and none of them has specifically investigated the DRR of interleukin (IL)-1 inhibitors on systemic JIA (sJIA). This study aims to describe IL-1 inhibitors DRR...

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Main Authors: Jurgen Sota, Antonella Insalaco, Rolando Cimaz, Maria Alessio, Marco Cattalini, Romina Gallizzi, Maria Cristina Maggio, Giuseppe Lopalco, Francesco La Torre, Claudia Fabiani, Manuela Pardeo, Alma Nunzia Olivieri, Paolo Sfriso, Carlo Salvarani, Carla Gaggiano, Salvatore Grosso, Claudia Bracaglia, Fabrizio De Benedetti, Donato Rigante, Luca Cantarini
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
systemic juvenile idiopathic arthritis
interleukin 1-beta
therapy
anakinra
canakinumab
drug retention rate
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01526/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01526/full

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