A Macromolecule Reversing Antibiotic Resistance Phenotype and Repurposing Drugs as Potent Antibiotics

A Macromolecule Reversing Antibiotic Resistance Phenotype and Repurposing Drugs as Potent Antibiotics

Abstract In order to mitigate antibiotic resistance, a new strategy to increase antibiotic potency and reverse drug resistance is needed. Herein, the translocation mechanism of an antimicrobial guanidinium‐functionalized polycarbonate is leveraged in combination with traditional antibiotics to affor...

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Bibliographic Details
Main Authors: Xin Ding, Chuan Yang, Wilfried Moreira, Peiyan Yuan, Balamurugan Periaswamy, Paola Florez deSessions, Huimin Zhao, Jeremy Tan, Ashlynn Lee, Kai Xun Ong, Nathaniel Park, Zhen Chang Liang, James L. Hedrick, Yi Yan Yang
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Advanced Science
Subjects:
antibiotics
combination therapy
drug repurposing
macromolecules
reversal of antibiotic resistance phenotype
Online Access:https://doi.org/10.1002/advs.202001374

Internet

https://doi.org/10.1002/advs.202001374

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