Prostate cancer cell lines under hypoxia exhibit greater stem-like properties.

Hypoxia is an important environmental change in many cancers. Hypoxic niches can be occupied by cancer stem/progenitor-like cells that are associated with tumor progression and resistance to radiotherapy and chemotherapy. However, it has not yet been fully elucidated how hypoxia influences the stem-...

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Bibliographic Details
Main Authors: Yuanyuan Ma, Dongming Liang, Jian Liu, Karol Axcrona, Gunnar Kvalheim, Trond Stokke, Jahn M Nesland, Zhenhe Suo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3247249?pdf=render