Prostate cancer cell lines under hypoxia exhibit greater stem-like properties.
Hypoxia is an important environmental change in many cancers. Hypoxic niches can be occupied by cancer stem/progenitor-like cells that are associated with tumor progression and resistance to radiotherapy and chemotherapy. However, it has not yet been fully elucidated how hypoxia influences the stem-...
Main Authors: | Yuanyuan Ma, Dongming Liang, Jian Liu, Karol Axcrona, Gunnar Kvalheim, Trond Stokke, Jahn M Nesland, Zhenhe Suo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3247249?pdf=render |
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