Ultra-deep sequencing of intra-host rabies virus populations during cross-species transmission.

One of the hurdles to understanding the role of viral quasispecies in RNA virus cross-species transmission (CST) events is the need to analyze a densely sampled outbreak using deep sequencing in order to measure the amount of mutation occurring on a small time scale. In 2009, the California Departme...

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Bibliographic Details
Main Authors: Monica K Borucki, Haiyin Chen-Harris, Victoria Lao, Gilda Vanier, Debra A Wadford, Sharon Messenger, Jonathan E Allen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3836733?pdf=render