Serum from human burn victims impairs myogenesis and protein synthesis in primary myoblasts

The pathophysiological response to a severe burn injury involves a robust increase in circulating inflammatory/endocrine factors and a hypermetabolic state, both of which contribute to prolonged skeletal muscle atrophy. In order to characterize the role of circulating factors in muscle atrophy follo...

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Bibliographic Details
Main Authors: Katie L Corrick, Michael J Stec, Edward K Merritt, Samuel T Windham, Steven J Thomas, James M Cross, Marcas M Bamman
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00184/full