The Endocytic Receptor Megalin and its Associated Proteins in Proximal Tubule Epithelial Cells

The Endocytic Receptor Megalin and its Associated Proteins in Proximal Tubule Epithelial Cells

Receptor-mediated endocytosis in renal proximal tubule epithelial cells (PTECs) is important for the reabsorption and metabolization of proteins and other substances, including carrier-bound vitamins and trace elements, in glomerular filtrates. Impairment of this endocytic process results in the los...

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Bibliographic Details
Main Authors: Shankhajit De, Shoji Kuwahara, Akihiko Saito
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Membranes
Subjects:
ARH
clathrin
ClC-5
cubilin
endocytosis
exosome
megalin
NHE3
trafficking
Online Access:http://www.mdpi.com/2077-0375/4/3/333

Internet

http://www.mdpi.com/2077-0375/4/3/333

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