When are pathogen genome sequences informative of transmission events?

Recent years have seen the development of numerous methodologies for reconstructing transmission trees in infectious disease outbreaks from densely sampled whole genome sequence data. However, a fundamental and as of yet poorly addressed limitation of such approaches is the requirement for genetic d...

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Bibliographic Details
Main Authors: Finlay Campbell, Camilla Strang, Neil Ferguson, Anne Cori, Thibaut Jombart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006885