SETDB-1: A Potential Epigenetic Regulator in Breast Cancer Metastasis

SETDB-1: A Potential Epigenetic Regulator in Breast Cancer Metastasis

The full epigenetic repertoire governing breast cancer metastasis is not completely understood. Here, we discuss the histone methyltransferase SET Domain Bifurcated Histone Lysine Methyltransferase 1 (SETDB1) and its role in breast cancer metastasis. SETDB1 serves as an exemplar of the difficulties...

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Bibliographic Details
Main Authors: Jacob Batham, Pek Siew Lim, Sudha Rao
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
breast cancer
cancer stem cells
therapy
resistance
recurrence
SETDB1
epigenetics
Online Access:https://www.mdpi.com/2072-6694/11/8/1143

Internet

https://www.mdpi.com/2072-6694/11/8/1143

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