Nitration of β-Lactoglobulin but Not of Ovomucoid Enhances Anaphylactic Responses in Food Allergic Mice.

We revealed in previous studies that nitration of food proteins reduces the risk of de novo sensitization in a murine food allergy model. In contrast, in situations with preformed specific IgE antibodies, in vitro experiments suggested an increased capacity of effector cell activation by nitrated fo...

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Main Authors: Susanne C Diesner, Cornelia Schultz, Chloé Ackaert, Gertie J Oostingh, Anna Ondracek, Caroline Stremnitzer, Josef Singer, Denise Heiden, Franziska Roth-Walter, Judit Fazekas, Vera E Assmann, Erika Jensen-Jarolim, Hanno Stutz, Albert Duschl, Eva Untersmayr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4425501?pdf=render