Genome-Wide Binding Analyses of HOXB1 Revealed a Novel DNA Binding Motif Associated with Gene Repression

Genome-Wide Binding Analyses of HOXB1 Revealed a Novel DNA Binding Motif Associated with Gene Repression

Knowledge of the diverse DNA binding specificities of transcription factors is important for understanding their specific regulatory functions in animal development and evolution. We have examined the genome-wide binding properties of the mouse HOXB1 protein in embryonic stem cells differentiated in...

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Bibliographic Details
Main Authors: Narendra Pratap Singh, Bony De Kumar, Ariel Paulson, Mark E. Parrish, Carrie Scott, Ying Zhang, Laurence Florens, Robb Krumlauf
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Developmental Biology
Subjects:
transcription factor
mouse Hox genes
DNA binding motif
HOXB1
PBX1
REST
Online Access:https://www.mdpi.com/2221-3759/9/1/6

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https://www.mdpi.com/2221-3759/9/1/6

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