Dietary Intake of Sulforaphane-Rich Broccoli Sprout Extracts during Juvenile and Adolescence Can Prevent Phencyclidine-Induced Cognitive Deficits at Adulthood.

Dietary Intake of Sulforaphane-Rich Broccoli Sprout Extracts during Juvenile and Adolescence Can Prevent Phencyclidine-Induced Cognitive Deficits at Adulthood.

Oxidative stress and inflammation play a role in cognitive impairment, which is a core symptom of schizophrenia. Furthermore, a hallmark of the pathophysiology of this disease is the dysfunction of cortical inhibitory γ-aminobutyric acid (GABA) neurons expressing parvalbumin (PV), which is also invo...

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Main Authors: Yumi Shirai, Yuko Fujita, Ryota Hashimoto, Kazutaka Ohi, Hidenaga Yamamori, Yuka Yasuda, Tamaki Ishima, Hiroyuki Suganuma, Yusuke Ushida, Masatoshi Takeda, Kenji Hashimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0127244

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https://doi.org/10.1371/journal.pone.0127244

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