Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression
<p>The decline in adaptive immunity, naïve T-cell output and a contraction in the peripheral T cell receptor (TCR) repertoire with age are largely attributable to thymic involution and the loss of critical cytokines and hormones within the thymic microenvironment. To assess the molecu...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2009-01-01
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| Series: | International Journal of Medical Sciences |
| Online Access: | http://www.medsci.org/v06p0051.htm |