Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome

<p>Abstract</p> <p>Background</p> <p>Host defense peptides are a critical component of the innate immune system. Human alpha- and beta-defensin genes are subject to copy number variation (CNV) and historically the organization of mouse alpha-defensin genes has been poor...

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Bibliographic Details
Main Authors: Dougan Gordon, Gilbert James GR, Brown Kelly L, Rehaume Linda M, Amid Clara, Hancock Robert EW, Harrow Jennifer L
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/606