Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy

SUMMARY Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease for which there is no cure and limited treatment options. Prednisone is currently the first line treatment option for DMD and studies have demonstrated that it improves muscle strength. Although prednisone has been used for t...

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Bibliographic Details
Main Authors: Ryan D. Wuebbles, Apurva Sarathy, Joe N. Kornegay, Dean J. Burkin
Format: Article
Language:English
Published: The Company of Biologists 2013-09-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/5/1175