Generating real-world evidence from unstructured clinical notes to examine clinical utility of genetic tests: use case in BRCAness

Generating real-world evidence from unstructured clinical notes to examine clinical utility of genetic tests: use case in BRCAness

Abstract Background Next-generation sequencing provides comprehensive information about individuals’ genetic makeup and is commonplace in oncology clinical practice. However, the utility of genetic information in the clinical decision-making process has not been examined extensively from a real-worl...

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Bibliographic Details
Main Authors: Yiqing Zhao, Saravut J. Weroha, Ellen L. Goode, Hongfang Liu, Chen Wang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Precision medicine
Real-world evidence
BRCA1/2
PARP inhibitor
Electronic health records
Natural language processing
Online Access:https://doi.org/10.1186/s12911-020-01364-y

Internet

https://doi.org/10.1186/s12911-020-01364-y

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