Mesenchymal Stromal Cells for Graft Versus Host Disease: Mechanism-Based Biomarkers

Mesenchymal Stromal Cells for Graft Versus Host Disease: Mechanism-Based Biomarkers

The immunosuppressive activity of mesenchymal stromal cells (MSCs) in graft versus host disease (GvHD) is well-documented, but their therapeutic benefit is rather unpredictable. Prospective randomized clinical trials remain the only means to address MSC clinical efficacy. However, the imperfect unde...

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Bibliographic Details
Main Authors: Tik Shing Cheung, Giuliana Minani Bertolino, Chiara Giacomini, Martin Bornhäuser, Francesco Dazzi, Antonio Galleu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
mesenchymal stromal cell
graft versus host disease
biomarker
apoptosis
efferocytosis
extracellular vesicles
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01338/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01338/full

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