Evolution of replicative DNA polymerases in archaea and their contributions to the eukaryotic replication machinery

The elaborate eukaryotic DNA replication machinery evolved from the archaeal ancestors that themselves show considerable complexity. Here we discuss the comparative genomic and phylogenetic analysis of the core replication enzymes, the DNA polymerases, in archaea and their relationships with the euk...

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Bibliographic Details
Main Authors: Kira S Makarova, Mart eKrupovic, Eugene V. Koonin
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00354/full