A novel strategy for enrichment and isolation of osteoprogenitor cells from induced pluripotent stem cells based on surface marker combination.

A novel strategy for enrichment and isolation of osteoprogenitor cells from induced pluripotent stem cells based on surface marker combination.

In this study, we developed a new method to stimulate osteogenic differentiation in tissue-nonspecific alkaline phosphatase (TNAP)-positive cells liberated from human induced pluripotent stem cells (hiPSCs)-derived embryoid bodies (EBs) with 14 days long TGF-β/IGF-1/FGF-2 treatment. TNAP is a marker...

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Bibliographic Details
Main Authors: Hiromi Ochiai-Shino, Hiroshi Kato, Takashi Sawada, Shoko Onodera, Akiko Saito, Tsuyoshi Takato, Takahiko Shibahara, Takashi Muramatsu, Toshifumi Azuma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4050034?pdf=render

Internet

http://europepmc.org/articles/PMC4050034?pdf=render

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