The utility of shallow RNA-Seq for documenting differential gene expression in genes with high and low levels of expression.

The sequencing depth necessary for documenting differential gene expression using RNA-Seq has been little explored outside of model systems. In particular, the depth required to analyze large-scale patterns of differential transcription factor expression is not known. The goal of the present study i...

Full description

Bibliographic Details
Main Authors: Joel Atallah, David C Plachetzki, W Cameron Jasper, Brian R Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24358338/?tool=EBI