Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection.

Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection.

Influenza virus causes a heterogeneous respiratory infectious disease ranging from self-limiting symptoms to non-resolving pathology in the lungs. Worldwide, seasonal influenza infections claim ~500,000 lives annually. Recent reports describe pathologic pulmonary sequelae that result in remodeling t...

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Bibliographic Details
Main Authors: Su Huang, Nick P Goplen, Bibo Zhu, In Su Cheon, Youngmin Son, Zheng Wang, Chaofan Li, Qigang Dai, Li Jiang, Min Xiang, Eva M Carmona, Robert Vassallo, Andrew H Limper, Jie Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223430

Internet

https://doi.org/10.1371/journal.pone.0223430

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