Early Exercise Protects the Blood-Brain Barrier from Ischemic Brain Injury via the Regulation of MMP-9 and Occludin in Rats

Early Exercise Protects the Blood-Brain Barrier from Ischemic Brain Injury via the Regulation of MMP-9 and Occludin in Rats

Early exercise within 24 h after stroke can reduce neurological deficits after ischemic brain injury. However, the mechanisms underlying this neuroprotection remain poorly understood. Ischemic brain injury disrupts the blood-brain barrier (BBB) and then triggers a cascade of events, leading to secon...

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Bibliographic Details
Main Authors: Yuling Zhang, Pengyue Zhang, Xiafeng Shen, Shan Tian, Yi Wu, Yulian Zhu, Jie Jia, Junfa Wu, Yongshan Hu
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:International Journal of Molecular Sciences
Subjects:
early exercise
cerebral ischemia and reperfusion
blood brain barrier
MMP-9
occludin
Online Access:http://www.mdpi.com/1422-0067/14/6/11096

Internet

http://www.mdpi.com/1422-0067/14/6/11096

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