Serum Concentrations of Cholinesterase Inhibitors in Patients With Alzheimer’s Dementia Are Frequently Below the Recommended Levels

Serum Concentrations of Cholinesterase Inhibitors in Patients With Alzheimer’s Dementia Are Frequently Below the Recommended Levels

BackgroundAcetylcholinesterase inhibitors (AChE-I) are recommended for the treatment of cognitive symptoms but also of behavioral and psychological symptoms in dementia. They are widely used not only in Alzheimer's disease, but also in other forms of dementia. Efficacy of treatment might depend...

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Bibliographic Details
Main Authors: Marion Ortner, Marion Stange, Heike Schneider, Charlotte Schroeder, Katharina Buerger, Claudia Müller, Bianca Dorn, Oliver Goldhardt, Janine Diehl-Schmid, Hans Förstl, Werner Steimer, Timo Grimmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer's disease
Alzheimer's dementia
cholinesterase inhibitors
serum concentration
therapeutic drug monitoring
treatment efficacy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00691/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00691/full

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