Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication
The replicative helicase unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. In eukaryotes, the replicative helicase is composed of the Cdc45 protein, the heterohexameric ring-shaped Mcm2-7 complex, and the tetrameric G...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-04-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/8/4/117 |