Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication

The replicative helicase unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. In eukaryotes, the replicative helicase is composed of the Cdc45 protein, the heterohexameric ring-shaped Mcm2-7 complex, and the tetrameric G...

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Bibliographic Details
Main Authors: Matthew P. Martinez, Amanda L. Wacker, Irina Bruck, Daniel L. Kaplan
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Genes
Subjects:
MCM
Online Access:http://www.mdpi.com/2073-4425/8/4/117