Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum.

There is a need to develop new effective immunoadjuvants for prophylactic or therapeutic vaccines against intracellular pathogens. The activation of Rho GTPases by bacterial cytotoxic necrotizing factor 1 (CNF1) elicits humoral protective responses against protein antigens. Here, we set out to inves...

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Bibliographic Details
Main Authors: Grégory Michel, Bernard Ferrua, Patrick Munro, Laurent Boyer, Nassim Mathal, Daniel Gillet, Pierre Marty, Emmanuel Lemichez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4892475?pdf=render