JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cells

JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cells

Abstract Background In view of the fact that JS-K might regulate ubiquitin E3 ligase and that ubiquitin E3 ligase plays an important role in the mechanism of CRPC formation, the goal was to investigate the probable mechanism by which JS-K regulates prostate cancer cells. Methods Proliferation inhibi...

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Bibliographic Details
Main Authors: Guobin Tan, Mingning Qiu, Lieqian Chen, Sai Zhang, Longzhi Ke, Jianjun Liu
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Cancer
Subjects:
Prostate cancer
JS-K
Ubiquitin E3 ligase
Apoptosis
Proliferation
Online Access:http://link.springer.com/article/10.1186/s12885-017-3351-0

Internet

http://link.springer.com/article/10.1186/s12885-017-3351-0

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