A Ferroptosis-Related Prognostic Signature Based on Antitumor Immunity and Tumor Protein p53 Mutation Exploration for Guiding Treatment in Patients With Head and Neck Squamous Cell Carcinoma

A Ferroptosis-Related Prognostic Signature Based on Antitumor Immunity and Tumor Protein p53 Mutation Exploration for Guiding Treatment in Patients With Head and Neck Squamous Cell Carcinoma

Background: Due to the lack of accurate guidance of biomarkers, the treatment of head and neck squamous cell carcinoma (HNSCC) has not been ideal. Ferroptosis plays an important role in tumor suppression and treatment of patients. However, tumor protein p53 (TP53) mutation may promote tumor progress...

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Bibliographic Details
Main Authors: Xin Fan, YangShaobo Ou, Huijie Liu, Liangzhen Zhan, Xingrong Zhu, Mingyang Cheng, Qun Li, Dongmei Yin, Lan Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
head and neck squamous cell carcinoma
ferroptosis
immune microenvironment
mutation
clinical treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.732211/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.732211/full

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