Behavioral Effects of a Potential Novel TAAR1 Antagonist

Behavioral Effects of a Potential Novel TAAR1 Antagonist

The trace amine associated receptor 1 (TAAR1) is a G-protein coupled receptor expressed in the monoaminergic regions of the brain, and represents a potential novel therapeutic target for the treatment of neurological disorders. While selective agonists for TAAR1 have been successfully identified, on...

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Bibliographic Details
Main Authors: Vincent M. Lam, Catharine A. Mielnik, Corey Baimel, Pieter Beerepoot, Stefano Espinoza, Ilya Sukhanov, Wendy Horsfall, Raul R. Gainetdinov, Stephanie L. Borgland, Amy J. Ramsey, Ali Salahpour
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
TAAR1
dopamine transporter (DAT)
cocaine
amphetamine
locomotor activity
electrophysiology
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00953/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00953/full

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