A peek into cancer-associated fibroblasts: origins, functions and translational impact
In malignant tumors, cancer cells adapt to grow within their host tissue. As a cancer progresses, an accompanying host stromal response evolves within and around the nascent tumor. Among the host stromal constituents associated with the tumor are cancer-associated fibroblasts, a highly abundant and...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-04-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/11/4/dmm029447 |