Granzyme K activates protease-activated receptor-1.

Granzyme K (GrK) is a trypsin-like serine protease that is elevated in patients with sepsis and acute lung inflammation. While GrK was originally believed to function exclusively as a pro-apoptotic protease, recent studies now suggest that GrK may possess other non-cytotoxic functions. In the contex...

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Bibliographic Details
Main Authors: Dawn M Cooper, Dmitri V Pechkovsky, Tillie L Hackett, Darryl A Knight, David J Granville
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3128063?pdf=render