Granzyme K activates protease-activated receptor-1.
Granzyme K (GrK) is a trypsin-like serine protease that is elevated in patients with sepsis and acute lung inflammation. While GrK was originally believed to function exclusively as a pro-apoptotic protease, recent studies now suggest that GrK may possess other non-cytotoxic functions. In the contex...
Main Authors: | Dawn M Cooper, Dmitri V Pechkovsky, Tillie L Hackett, Darryl A Knight, David J Granville |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3128063?pdf=render |
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