Mutational analysis of human lipoprotein lipase by carboxy-terminal truncation
We have previously reported a Trp382 (TGG)–>stop (TGA) mutation that causes familial lipoprotein lipase (LPL) deficiency. Expression study of the Trp382–>stop mutant showed that the truncated LPL was catalytically inactive with a marked reduction in the expressed mass. To investigate the minim...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1993-10-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520357394 |