DNA methylation markers and serum α-fetoprotein level are prognostic factors in hepatocellular carcinoma

Introduction. Hypermethylation of relevant genes may affect the prognosis of patients with cancer. The purpose of this study was to analyze whether methylation of the promoter regions of cell cycle regulators as well as elevated α-Fetoprotein (AFP) levels are useful prognostic factors for patients w...

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Bibliographic Details
Main Authors: Jin-Ching Lin, Yao-Chung Wu, Cheng-Chung Wu, Pei-Yin Shih, Wen-Yi Wang, Yi-Chih Chien, PhD.
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Annals of Hepatology
Subjects:
p21
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119311718