Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody.
Identifying functionally critical regions of the malaria antigen AMA1 (apical membrane antigen 1) is necessary to understand the significance of the polymorphisms within this antigen for vaccine development. The crystal structure of AMA1 in complex with the Fab fragment of inhibitory monoclonal anti...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-09-01
|
| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC2323298?pdf=render |