Bmi-1 absence causes premature brain degeneration.

Bmi-1 absence causes premature brain degeneration.

Bmi-1, a polycomb transcriptional repressor, is implicated in cell cycle regulation and cell senescence. Its absence results in generalized astrogliosis and epilepsy during the postnatal development, but the underlying mechanisms are poorly understood. Here, we demonstrate the occurrence of oxidativ...

Full description

Bibliographic Details
Main Authors: Guangliang Cao, Minxia Gu, Min Zhu, Junying Gao, Ying Yin, Charles Marshall, Ming Xiao, Jiong Ding, Dengshun Miao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282795?pdf=render

Internet

http://europepmc.org/articles/PMC3282795?pdf=render

Similar Items