Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

Mounting evidence supports a fundamental role for Ca2+ dysregulation in astrocyte activation. Though the activated astrocyte phenotype is complex, cell-type targeting approaches have revealed a number of detrimental roles of activated astrocytes involving neuroinflammation, release of synaptotoxic f...

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Bibliographic Details
Main Authors: Pradoldej Sompol, Christopher M. Norris
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
Ca2+
glia
dementia
astrocytes
neuroinflammation
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00199/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00199/full

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