Choline administration attenuates aspects of the dystrophic pathology in mdx mice
Summary: Background & aims: Dystrophic muscle fibres are fragile and prone to breakage, leading to impaired Ca2+ homeostasis and excessive inflammation, resulting in muscle wasting and weakness. Choline, an essential water-soluble nutrient, is involved in multiple biological processes, includin...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-04-01
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Series: | Clinical Nutrition Experimental |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352939318300897 |