Cellular effects of everolimus and sirolimus on podocytes.

Everolimus (EVL) and Sirolimus (SRL) are potent immunosuppressant agents belonging to the group of mammalian target of rapamycin (mTOR) inhibitors used to prevent transplant rejection. However, some patients develop proteinuria following a switch from a calcineurin inhibitor regimen to mTOR inhibito...

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Bibliographic Details
Main Authors: Sandra Müller-Krebs, Lena Weber, Julia Tsobaneli, Lars P Kihm, Jochen Reiser, Martin Zeier, Vedat Schwenger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829970?pdf=render