Fe(II)/Et3N-Relay-catalyzed domino reaction of isoxazoles with imidazolium salts in the synthesis of methyl 4-imidazolylpyrrole-2-carboxylates, its ylide and betaine derivatives

Fe(II)/Et3N-Relay-catalyzed domino reaction of isoxazoles with imidazolium salts in the synthesis of methyl 4-imidazolylpyrrole-2-carboxylates, its ylide and betaine derivatives

A simple approach was developed for the synthesis of methyl 4-imidazolylpyrrole-2-carboxylates from easily available compounds, 5-methoxyisoxazoles and phenacylimidazolium salts under hybrid Fe(II)/Et3N relay catalysis. The products were easily transformed into the corresponding 3-(5-methoxycarbonyl...

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Bibliographic Details
Main Authors: Ekaterina E. Galenko, Olesya A. Tomashenko, Alexander F. Khlebnikov, Mikhail S. Novikov, Taras L. Panikorovskii
Format: Article
Language:English
Published: Beilstein-Institut 2015-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
imidazole
isoxazole
NHC carbene
pyrrole-2-carboxylate
relay catalysis
Online Access:https://doi.org/10.3762/bjoc.11.189

Internet

https://doi.org/10.3762/bjoc.11.189

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