Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

Syngeneic mouse models for glioblastoma (GBM) cannot fully recapitulate clinical findings and response to therapy in patients. Here the authors perform a comprehensive immune profiling of different syngeneic GBM tumour models and compare it with the immune landscape of GBM patients to identify simil...

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Bibliographic Details
Main Authors: Jasneet Kaur Khalsa, Nina Cheng, Joshua Keegan, Ameen Chaudry, Joseph Driver, Wenya Linda Bi, James Lederer, Khalid Shah
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17704-5