Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance

Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance

Negative DNA supercoiling allows chromosome condensation and facilitates DNA unwinding, which is required for the occurrence of DNA transaction processes, i.e., DNA replication, transcription and recombination. In bacteria, changes in chromosome supercoiling impact global gene expression; however, t...

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Bibliographic Details
Main Authors: Marcin Jan Szafran, Martyna Gongerowska, Tomasz Małecki, Marie Elliot, Dagmara Jakimowicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
TopA
DNA supercoiling
Streptomyces
Streptomyces coelicolor
gene regulation
topoisomerase
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01605/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01605/full

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