The association of clinical phenotypes to known AD/FTD genetic risk loci and their inter-relationship.

To elucidate how variants in genetic risk loci previously implicated in Alzheimer's Disease (AD) and/or frontotemporal dementia (FTD) contribute to expression of disease phenotypes, a phenome-wide association study was performed in two waves. In the first wave, we explored clinical traits assoc...

Full description

Bibliographic Details
Main Authors: Qingqin S Li, Chao Tian, 23andMe Research Team, David Hinds, Guy R Seabrook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241552