MicroRNA Let-7d-3p Contributes to Cardiac Protection via Targeting HMGA2

MicroRNA Let-7d-3p Contributes to Cardiac Protection via Targeting HMGA2

We tested the hypothesis that Let-7d-3p contributes to cardiac cell protection during hypoxic challenge. Myoblast H9c2 cells and primary neonatal rat ventricular cardiomyocytes (NRVM) were transfected with five selected miRNA mimics. Both cell lines were subjected to 0.2% oxygen hypoxia. The protect...

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Bibliographic Details
Main Authors: Lee Lee Wong, Eng Leng Saw, Jia Yuen Lim, Yue Zhou, Arthur Mark Richards, Peipei Wang
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA
cardiac protection
apoptosis
Let-7d-3p
HMGA2
Online Access:https://www.mdpi.com/1422-0067/20/7/1522

Internet

https://www.mdpi.com/1422-0067/20/7/1522

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