O-GlcNAcylation Affects the Pathway Choice of DNA Double-Strand Break Repair

O-GlcNAcylation Affects the Pathway Choice of DNA Double-Strand Break Repair

Exposing cells to DNA damaging agents, such as ionizing radiation (IR) or cytotoxic chemicals, can cause DNA double-strand breaks (DSBs), which are crucial to repair to maintain genetic integrity. O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is a post-translational modification (PTM), whic...

Full description

Bibliographic Details
Main Authors: Sera Averbek, Burkhard Jakob, Marco Durante, Nicole B. Averbeck
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
O-GlcNAcylation
DNA-DSB repair
chromatin remodeling
high LET
particle irradiation
ionizing radiation
Online Access:https://www.mdpi.com/1422-0067/22/11/5715

Internet

https://www.mdpi.com/1422-0067/22/11/5715

Similar Items