New Drosophila Circadian Clock Mutants Affecting Temperature Compensation Induced by Targeted Mutagenesis of Timeless

New Drosophila Circadian Clock Mutants Affecting Temperature Compensation Induced by Targeted Mutagenesis of Timeless

Drosophila melanogaster has served as an excellent genetic model to decipher the molecular basis of the circadian clock. Two key proteins, PERIOD (PER) and TIMELESS (TIM), are particularly well explored and a number of various arrhythmic, slow, and fast clock mutants have been identified in classica...

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Bibliographic Details
Main Authors: Samarjeet Singh, Astrid Giesecke, Milena Damulewicz, Silvie Fexova, Gabriella M. Mazzotta, Ralf Stanewsky, David Dolezel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Physiology
Subjects:
circadian clock
reverse genetics
screening
candidate genes
temperature compensation
CRISPR-CAS9
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01442/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01442/full

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