The intracellular region of Notch ligands: does the tail make the difference?
<p>Abstract</p> <p/> <p>The cytoplasmic tail of Notch ligands drives endocytosis, mediates association with proteins implicated in the organization of cell-cell junctions and, through regulated intra-membrane proteolysis, is released from the membrane as a signaling fragment....
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-07-01
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Series: | Biology Direct |
Online Access: | http://www.biology-direct.com/content/2/1/19 |