The intracellular region of Notch ligands: does the tail make the difference?

<p>Abstract</p> <p/> <p>The cytoplasmic tail of Notch ligands drives endocytosis, mediates association with proteins implicated in the organization of cell-cell junctions and, through regulated intra-membrane proteolysis, is released from the membrane as a signaling fragment....

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Bibliographic Details
Main Authors: Pongor Sándor, Ivanova Neli, Popovic Matija, De Biasio Alfredo, Pintar Alessandro
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/2/1/19