P2X7 Receptor in Hematological Malignancies

The P2X7 receptor is an ion channel gated by the nucleotide ATP, known for its role in immune responses and recently emerging as a critical onco-promoting factor. Lymphocytes, myeloid cells, and their precursors were among the first cells proved to express a functional P2X7 receptor; therefore, it i...

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Bibliographic Details
Main Authors: Elena De Marchi, Anna Pegoraro, Elena Adinolfi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ATP
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.645605/full